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基本信息 姓名 周景文 职称 教授 学历/学位 研究生/博士 联系电话 0510-85918312 电子邮箱 zhoujw1982@jiangnan.

edu.cn 长期从事微生物代谢工程研究,主要承担《代谢途径工程》和《酶工程与技术》课程的 讲授工作.近年来共发表高水平研究论文78篇,累计影响因子达306,他引682次,出版 专著(或教材)2部;

申请发明专利32项,授权发明专利22项,其中国际发明专利3项;

主持包括十二五863重点项目课题、国家自然基金面上项目等在内的省部级科研项目9 项;

获得国家技术进步二等奖(2015,2/6)等奖6项.现为江苏省特聘教授、教育部新 世纪优秀人才,《生物工程学报》编委. 学习工作经历(自本科填起) 个人简介 1999-2003 华中农业大学,食品科学与工程专业,工学学士 2003-2006 华中农业大学,微生物学专业,理学硕士 2006-2009 江南大学,生物工程专业,工学博士 2009-至今 江南大学,留校任教 其中: 2012-2013 美国哈佛大学,化学与化学生物学系,博士后 [1] Yongkun Lv, Xiaozhong Chen, Guocheng Du, Jingwen Zhou*, Jian Chen*. Engineering of an H2O2 auto-scavenging in vivo cascade for pinoresinol production. Biotechnology and Bioengineering, 2017. 114(9): 2066-2074. [2] Shenghu Zhou, Renpeng Ding, Jian Chen, Guocheng Du, Huazhong Li*, Jingwen Zhou*. Obtaining a panel of cascade promoter-5′-UTR complexes in Escherichia coli. ACS Synthetic Biology, 2017. 6(6): 1065-1075;

[3] Peng Zhang, Guocheng Du, Huijun Zou, Guangfa Xie, Jian Chen J, Zhongping Shi*, Jingwen Zhou*. Mutant Potential Ubiquitination Sites in Dur3p Enhance the urea and ethyl carbamate reduction in a model rice wine system. Journal of Agricultural and Food Chemistry, 2017. 65(8): 1641-1648. [4] Jingwen Zhou*, Kui Wang, Sha Xu, Junjun Wu, Peiran Liu, Guocheng Du, Jianghua Li*, Jian Chen. Identification of membrane proteins associated with phenylpropanoids tolerance and transport in Escherichia coli BL21. Journal of Proteomics. 2015, 113: 15-28. [5] Junjun Wu, Oliver Yu, Guocheng Du, Jingwen Zhou*, Jian Chen*. Fine-tuning of fatty acid pathway by synthetic antisense RNA for enhanced (2S)-naringenin production from L-tyrosine in Escherichia coli. Applied and Environmental Microbiology. 2014, 80(23):7283-7292. 主要代表性成果:

一、论文(论著)发表情况 [6] Saijie Zhu, Junjun Wu, Guocheng Du, Jingwen Zhou*, Jian Chen*. Efficient synthesis of eriodictyol from L-tyrosine in Escherichia coli. Applied and Environmental Microbiology. 2014, 10(80): 3072-3080. [7] Lili Gao, Yudong Hu, Jie Liu, Guocheng Du, Jingwen Zhou*, Jian Chen*. Stepwise metabolic engineering of Gluconobacter oxydans WSH-003 for the direct production of 2-keto- L-gulonic acid from D-sorbitol. Metabolic Engineering. 2014, 24: 30C37. [8] Shaohui Zhao, Xinrui Zhao, Huijun Zou, Jianwei Fu, Jian Chen, Jingwen Zhou*, Guocheng Du*. Comparative proteomic analysis of Saccharomyces cerevisiae under different nitrogen sources. Journal of Proteomics. 2014, 101: 102-112. [9] Jingwen Zhou*, Guocheng Du, Jian Chen. Novel fermentation processes for manufacturing plant natural products. Current Opinion in Biotechnology. 2014. 25: 17-23. [10] Xinrui Zhao, Guocheng Du*, Huijun Zou, Jianwei Fu, Jingwen Zhou*, Jian Chen. Metabolic engineering of the regulators in nitrogen catabolite repression to reduce the production of ethyl carbamate in a model rice wine system. Applied and Environmental Microbiology. 2014, 80(1): 392-398. [11] Xinrui Zhao, Guocheng Du*, Huijun Zou, Jianwei Fu, Jingwen Zhou*, Jian Chen. Progress in preventing the accumulation of ethyl carbamate in alcoholic beverages. Trends in Food Science & Technology. 2013, 32: 97-107. [1] Jian Chen, Jingwen Zhou, Hongwei Guo, Guocheng Du. A genetically engineered Yarrowia lipolytica with enhanced extracellular secretion of a-ketoglutarate,US 14/142,897;