XLS《Table1》

10542 , hepatitisBvirusxinteractingprotein , InteractionofhepatitisBviraloncoproteinwithcellulartargetHBXIPdysregulatescentrosomedynamicsandmitoticspindleformation. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=18032378[uid]

18492607 , HBx , Xprotein , phosphorylation , phosphorylate , CHK1 , CHEK1 ,

1111 , CHK1checkpointhomolog(S.pombe) , HBximpairedtheATRdependentphosphorylationofChk1andmonoubiquitinationofFANCD2. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=18492607[uid]

11325602 , HBx , Xprotein , activated , activate , IKK , CHUK ,

1147 , conservedhelix-loop-helixubiquitouskinase , However,themajorityofHBxislocalizedtothecytoplasmwhereitinteractswithandstimulatesproteinkinasessuchasproteinkinaseC,Januskinase/STAT,IKK,PI-3-K,stress-activatedproteinkinase/JunN-terminalkinase,andproteinkinaseB/Akt. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=11325602[uid]

16534844 , coreprotein , coreprotein , interacting , interact , chemokine(C-Cmotif)receptor5 , CCR5 ,

1234 , chemokine(C-Cmotif)receptor5 , RESULTS:Eighteencolonieswereobtainedandsequenced,includinghypermethylatedincancer2(3colones),eukaryotictranslationelongationfactor2(2colones),acetyl-coenzymeAsynthetase3(1colone),DNApolymerasegamma(1colone),putativetranslationinitiationfactor(1colone),chemokine(C-Cmotif)receptor5(1colone),mitochondrialribosomalproteinL41(1colone),kyotbindingproteingenes(1colone),RanBPM(1colone),HBeAg-bindingprotein3(1colone),programmedcelldeath2(1colone).Fournewgeneswithunknownfunctionwereidentified.CONCLUSION:SuccessfulcloningofgenesofHBVcoreproteininteractingproteinsinleukocytesmayprovidesomenewcluesforstudyingthebiologicalfunctionsofHBVcoreprotein. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=16534844[uid]

18449922 , HBx , Xprotein , increased , increase , collagenI , COL1A1 ,

1277 , collagen,typeI,alpha1 , BothhumanprimaryHSCsandratHSCsexposedtoconditionedmediumfromHBx-expressinghepatocytesshowedincreasedexpressionofcollagenI,connectivetissuegrowthfactor,alphasmoothmuscleactin,matrixmetalloproteinase-2,andtransforminggrowthfactor-beta(TGF-beta),togetherwithanenhancedproliferationrate. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=18449922[uid]

11170386 , Xprotein , Xprotein , phosphorylation , phosphorylate , CREB , CREB1 ,

1385 , cAMPresponsiveelementbindingprotein1 , HepatitisBvirusXproteinactivatestranscriptionbybypassingCREBphosphorylation,notbystabilizingbZIP-DNAcomplexes. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=11170386[uid]

10590094 , Xprotein , Xprotein , interacts , interact , CREB , CREB1 ,

1385 , cAMPresponsiveelementbindingprotein1 , ThehepatitisBvirusXprotein(pX)interactsdirectlywiththebZiptransactivatorCREBandthebZiprepressorsICERIIgammaandATF3,increasingtheirDNA-bindingaffinityinvitroandtheirtranscriptionalefficacyinvivo. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=10590094[uid]

12876451 , Xprotein , Xprotein , interaction , interact , CREB , CREB1 ,

1385 , cAMPresponsiveelementbindingprotein1 , Acarboxy-terminalregionofthehepatitisBvirusXproteinpromotesDNAinteractionofCREBandmimicsthenativeproteinfortransactivationfunction. , http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&

cmd=search&

term=12876451[uid]

1827531 , Xprotein , Xprotein , interactions , interact , CREB , CREB1 ,

1385 , cAMPresponsiveelementbindingprotein1 , HBVXprotein........