PDF《中草药生物质炼制工程》

陈洪章 等/中草药生物质炼制工程 Chinese Journal of Biotechnology http://journals.

im.ac.cn/cjbcn June 25, 2014, 30(6): 801?815 DOI: 10.13345/j.cjb.140065 ?2014 Chin J Biotech, All rights reserved Received: January 28, 2014;

Accepted: March 7,

2014 Supported by: Special funds of the Science and technology innovation base for Beijing Key Laboratory of Biomass Refining Engineering (No. Z13111000280000), National Natural Science Foundation of China (No. 21206176), National Basic Research and Development Program of China (973 Program) (No. 2011CB707401). Corresponding author: Hongzhang Chen. Tel/Fax: +86-10-82627071;

E-mail: [email protected] 生物质炼制工程北京市重点实验室

2013 年度科技创新基地培育与发展工程专项项目 (No. Z13111000280000), 国家自然科学基金 项目 (No. 21206176), 国家重点基础研究发展计划 (973 计划) (No. 2011CB707401) 资助. 网络出版时间:2014-04-02 网络出版地址:http://www.cnki.net/kcms/doi/10.13345/j.cjb.140065.html

801 生物工程学报中草药生物质炼制工程 陈洪章,隋文杰 中国科学院过程工程研究所 生物质炼制工程北京市重点实验室,北京

100190 陈洪章, 隋文杰. 中草药生物质炼制工程. 生物工程学报, 2014, 30(6): 801?815. Chen HZ, Sui WJ. Biorefinery engineering for Chinese herbal medicines: a review. Chin J Biotech, 2014, 30(6): 801?815. 摘要: 目前我国中药产业面临资源紧张、药材利用率低、加工过程浪费严重等问题,究其原因主要是单一 药效成分利用、加工转化技术落后所致.针对上述问题,从生物质炼制角度,综述了实现中草药资源高效利用 的原料预处理、提取、转化及残渣后处理等

4 个关键单元操作中主要技术的研究进展,并指出中草药生物质炼 制工程发展趋势与前景. 关键词: 中草药,生物质炼制,预处理,提取,生物转化 Biorefinery engineering for Chinese herbal medicines: a review Hongzhang Chen, and Wenjie Sui Beijing Key Laboratory of Biomass Refining Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China Abstract: The resource limitation, ineffective utilization and severe waste generated during processing restrict the sustainable development of the Chinese herbal medicine industry. The main reasons lie in insufficient utilization of medicinal components as well as few and outdated technologies. Integration and optimization of serial technologies including pretreatment, extraction, conversion and waste treatment are the keys to solve these issues. In this article, the 特邀综述 ISSN 1000-3061 CN 11-1998/Q Chin J Biotech June 25,

2014 Vol.30 No.6 http://journals.im.ac.cn/cjbcn

802 updated research progress and technology development of biorefinery engineering for herbal medicines are reviewed. Guided by multi-products oriental fractionation refining, Chinese herbal medicine refinery technical system is constructed relied on advanced refinery technology platforms. Keywords: Chinese herbal medicine, biorefinery engineering, pretreatment, extraction, bioconversion 在人口老龄化、全球医疗体制改革、保健 养生及 回归自然 潮流的影响下, 越来越多的目 光聚焦到传统中草药及其保健制剂.凭借低毒 性、疗效确切、不易产生耐药性和双向调节等 诸多优势,中草药正逐渐为世界各国接受和认 可,并展示出广阔的发展前景.然而随着对其 需求的不断增长,我国中草药资源面临日益紧 缺的现状,同时面对药材利用率低、浪费严重 等问题. 目前我国处于濒危状态的近