PDF《奥地利纳米科技》

System Integration SENSOR DEVELOPMENT AIT Molecular Diagnostics experts are committed to developing highly sensitive nano-biosensors for analyzing liquids such as serum or saliva. AIT draws on its extensive expertise in the development and fabrication of nanosensors based on electrochemical electrodes, giant and tunneling magneto resistance, and integrated optical waveguides to design sophisticated lab-on-a-chip systems. SYSTEM INTEGRATION As portable molecular diagnostics depend on miniaturized and automated devices with superior analytical performance, AIT has built up profound expertise in the integration of biomarkers, sensors, micro fluidics, reactors, thermal management and readout electronics for such systems. The overall diagnostic system concept needs to be considered at a very early stage of sensor development and assay design. Our approach to system integration includes optimizing component interaction, system packaging, reagent storage and handling, interfaces for modular devices and signal processing. MICROFLUIDICS We investigate and develop liquid-based systems, e.g. for serum or saliva analysis, integrating reagent storage and the automation of fluidic protocols. A special focus lies on the integration of customized third party sensors. Fabrication takes place at the AIT Center for Thin Film Technology, which specializes in heterogeneous integration and precision assembly of different materials and components. AIT also develops functional thin films and coatings and uses the new possibilities offered by nanotechnology for systems and tools in biomedical diagnostics, lab-on-a-chip systems and sensors. 1. AIT C 奥地利科技研究院 Existing international cooperations: ?mnt-era.net Projekt MinoLab Miniaturised lab-on-a-chip system for the point-of-care analysis of infectious diseases - The MinoLab consortium will provide a novel point-of-care magnetic-bead-based lab-on-a-chip diagnostic platform that is rapid, portable, easy to perform and reliable;

the initial target application will be sepsis. This platform can straightforwardly be operated by untrained personnel directly at the bedside. The system will consist of a single-test disposable and an analyser called a MAZER. The MAZER consists of the mechanic and electronic components that control the processes on the disposable (a microfluidic cartridge), acquires and manages the data, and displays the final results. The micro-fluidic disposable contains appropriate reagents such as buffer solutions, enzymes and biological marker probes such as oligonucleotides or monoclonal antibodies. http://www.mnt-era.net/mnt-era-net-success-stories/2009-MinoLab%20_Public_.pdf ?FP-7 Projekt NAMDIATREAM Nanotechnological toolkits for multi-modal disease diagnostics a........