PDF《药学快讯》

s box of questions concerning the role of pre- and early post-natal nutrition as a critical determinant of chronic diseases throughout life. The ultimate goal is to elucidate the chronologic sequence of early-life events and the specific molecular mechanisms linking hypertriglyceridemia, insulin resistance, and the inflammation seen in obesity and asthma, which may open a new chapter in the management of these medical conditions that are among the most prevalent today. http://www.sciencedaily.com/releases/2010/09/100916121324.htm New Bioprosthetic-Tissue Heart Valve for Severe Aortic Stenosis Shown to Save Lives, Researchers Say ScienceDaily (Sep. 23, 2010) ― Implantation of a new bioprosthetic-tissue valve into the hearts of patients who have severe aortic stenosis and are too sick or too old for open-heart surgery has been found to both save lives and improve the quality of those lives, according to a new multicenter study, published online in the New England Journal of Medicine. The study is also being presented at the Transcatheter Cardiovascular Therapeutics Conference in Washington, D.C. on Sept. 23.

6 This is exciting because it does save lives and is a major medical paradigm shift, said D. Craig Miller, MD, the Thelma and Henry Doelger Professor of Cardiovascular Surgery at the Stanford University School of Medicine and one of the manuscript'

s principal authors. These patients were really sick with a fatal problem, and now they'

re feeling better and staying out of the hospital. Before, there was nothing we could really offer them. Stanford University Medical Center was one of

21 institutions to participate in the study, known as the PARTNER Trial. It is the first randomized clinical trial comparing the efficacy of using a transcatheter heart valve called TAVI -- which is implanted percutaneously through an artery in the groin directly into the beating heart -- with routine medical therapy, which includes aortic balloon valvuloplasty to relieve symptoms. The trial was sponsored b........