编辑: kr9梯 | 2015-09-03 |
766 Histone Deacetylases and Gene Repression LOCUS D (FLD), both in vitro and in vivo (Yu et?al., 2011). FLD is a Lysine Specific Demethylase1 (LSD1)-type histone demethylase that remove methyl groups from mono- and dimethylated histone H3K4 (Jiang et? al., 2007). Increased levels of histone H3 acetylation and H3K4 trimethylation at FLC, MAF4, and MAF5, the key repressors of flowering, were found in both hda6 and fld mutan........