PDF《Chapter 2》

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responsiveness of a stem cell. It is worth mentioning that although the steady-state number of neural stem cells at any given stage of development is the result of the equilibrium between proliferation, differentiation, migration and survival of these cells, this chap- ter will focus only on the experimental evidence on extracellular factors and intracellular molecules affecting proliferation of neural stem cells and multi- potent progenitors. This has been a very challenging task and although we have attempted to include several studies in this area, the overwhelming body of available literature has hindered our attempts to be exhaustive. Extracellular Factors Affecting........