PDF《生物颗粒光声功率谱的有限元数值》

参会者:李勇 晋中学院 方晖 深圳大学 生物颗粒光声功率谱的有限元数值 模拟研究 COMSOL CONFERENCE

2016 上海 The

2016 COMSOL Conference,Shanghai 山西Jinzhong University is a local university.

Taiyuan Shanxi Jinzhong University Located in Shanxi Province of china. Jinzhong University Beautiful campus Friendly and hospitable Welcome to our university Lecture outline 1. Research Background 2. Current Research 3. Research Prospects Research Background 研究目的和意义 结构 Photoacoustic effect 光声效应原理图 Yao J, Wang L V. Photoacoustic tomography: fundamentals, advances and prospects[J]. Contrast media & molecular imaging, 2011, 6(5): 332-345. Research Background 光声显微技术(PAM) AR-PAM OR-PAM Research Background 细胞核 Research Background 光声显微技术(PAM) 光声显微技术(PAM) Measurement Theory Research Background Lecture outline 1. Research Background 2. Current Research 3. Research Prospects 椭球坐标系Our group's main research 2D Axisymmetric Model

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90 0 Our group's main research Modeling Interfaces The transient acoustics module is used .The model assumes the biological particles absorbed the laser energy uniformly and instantaneously and was within thermal and stress confinement conditions. The pressure in the biological particle was set to unity and the surrounding coupling fluid pressure was set to zero. P(t=0)=1 P(t=0)=0 Modeling Parameters The parameters used in the model: 血红细胞(扁椭球) MCF7细胞核(长椭球) 长轴 短轴 等体积球形直径 内部密度 周围液体的密度 内部声速 周围液体声速 颗粒中心到最外层半径 10um 20um Our group's main research Boundary Conditions and Mesh 1.球面辐射边界. 2.A mixed mapped and triangular Mesh is used to mesh the domain. Presure Amplitude Frequency(MHz) Sphere RBC Oblate Red blood cell

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00 Red blood cell 100MHz 300MHz 500MHz 800MHz 1000MHz 1200MHz Red blood cell Time(ns) Pressure(a.u)

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90 0 MFC7 cell nuclei Lecture outline 1. Research Background 2. Current Research 3. Research Prospects 1. 3D Model. 2. 多物理场耦合:The electromagnetic wave equation、 transient heat transfer 、an acoustic pressure