PDF《。uÖºÙ¼TWTÕ ß­,》

&'()*++, Journal of Ningxia Medical University !

35 "

2 #

2013 $

2 % -.

/0:

1674 - 6309( 2013)

02 -

0142 -

04 ・ zH・ ???{?ü??d??7*?@A4?eBCD 4bc

1 , Fdc

1 , ,ef

2 , g h

2 ( 1. )* 750004;

2. J?($67"2, J? 430060) EF: GB B??E(O?_???u?`m?>WXY.HI ? SD ??(O

24 ?abc_E`e、 ??e( chronic unpredicted mild stress, CUMS e) BK?Le, re

8 ?.k47???E?e(O*??_$9:, ????u?`mW?>.JK CUMS e(O8??、 ê? 0. 05) .NOPF???9 CUMS e??rQKu?`m(Acet - Tub)?>bh, RstK u?`m( Tyr - Tub) ?>?i, ?E`e?P < 0. 01) ;

3K?L???, Acet - Tub ? >?i, Tyr - Tub ?>bh, ? CUMS e?P < 0. 01) .JL ??;

%????B? ?U?i(O??u?K?WiE?, ??23%8?, K?L%\úL??Wu???, %U?*S_? _Wc?b?. MNO: ??;

%????B??;

??;

???T;

u?`m PQRS0: R971 -TUVW: A XYZ#:

2012 -06 -11 [\]G: "(÷2?U( 2012BAI01B00) ^_`a: ?$ê(

1973 - ), ?, ??"?, k?, k????? Q, ??*S@?ì?f?b???. p WHO °,"???V"Wu?iE?W%[?? [ 5,

7 - 10].?&, ?? u?K?iE?W ??¤°, u?`m?>W?K?*S_?_ ú??!Rk/?W°K, ??A;

?W.ì í, ???J?B?? (CUMS)LM, ?Y#p??'(??u?K? iE? ? ?,E F * S ? ? f Q W % U c ? b?.

1 bcdHI 1.

1 47ce

24 ?!"

200 ~ 250g W(?g??? SD ( O( 247iù-?? n) , k?/ /v6_ 12h / 12h ( ?`?? 7:

00 ~ 19: 00) ¨??4??{|

1 v.1 v??[ab ????(Oc_?e, re

8 ?: ( 1)E`e, ?lmE` + Q?ìz??;

( 2)CUMS e, ?? ?;

%????B??(CUMS)+ Q?ìz? ?;

( 3) K?Le, ? CUMS + K?L?\. 1.

2 47ló 1. 2.

1 CUMS 47LMW?_ rGabZ?

1 W??\?47e(O, tu\? 21d, ZO]x y 45℃ 24h, O]~^ 15min, C?_r

24 h, 4℃ ?z-o`?? 5min, 42℃ ?z-?? 5min, ? _w? 2h, ?z 24h, ?? 24h, ?a 1min, 6u? ` 36h, b??\ 1min, c??d? 30min w.r W\?;

0tuWXY 1. 2.

3 iù?_$?? k47??d#?c 0E

3 e(O*?

2 s?_$??. ( 1)DzMc47: 47?(O*?Dz4 ?? ? B.? z

12 h ? (20:00 ~ 8:00 ) ,k 8:

00 ~ 10:

00 *?DzMc47.d((O?5 ?>cW

2 fz,

1 f_ 1% gD??, l f_(O G^h[z.2 h ?, ?/ 8?!?h> * 100% ) . ( 2)ià47: ià(N_

120 cm *

90 cm *

35 cm, 47k 10:

00 ~ 16:

00 *?.?(O?, ià-?, \[iù?_?i??K?(Ethovi sion 3. 0)S;

ùc?(OkiàV 10min W? _, ?à9???_(OkiàVW8??、 ?ià?_$ ?? 3??$c?, 47??e(OWDzMc ?iàP >

0 05) , ,? 1. e

1 h*?qrk@A+JK??(x±s) 9:?? E`e CUMS e K?Le F ? P ? Dz3&>/ % 80.

21 ± 7.

12 81.

33 ± 6.

82 79.

14 ± 7.

10 0.

067 0.

938 8??/ cm 9844.

33 ± 989.

43 10228.

32 ± 1087.

87 9972.

25 ± 992.

49 0.

231 0.

773 ê??ià?_$ 9:???? CUMS e(OIi????, ?|?/.D zMc、 8