编辑: 865397499 | 2019-07-10 |
com Tel. +86-574-88222391 Fax. +86-574-88222957 工作经历及教育背景 9/2013- 至今 副教授,浙江万里学院 9/2008- 8/2013 讲师,浙江万里学院 9/2005- 8/2008 助教,浙江万里学院 9/2013- 至今 在读博士,渔业资源,宁波大学,宁波 9/2002- 6/2005 硕士,细胞生物学,浙江大学,杭州 9/1998- 6/2002 本科,生物技术,浙江大学,杭州 教学经历 ? 浙江万里学院 硕士课程:Z1002 生物分离工程(2012 - 至今). 本科课程:1F15025 植物学与植物生理学(2005 - 至今). 1F11043 生化分离工程(2006 -至今). 1F11235 生化实验技术(2005 - 至今). 1F10527 基因工程实验技术(2006 - 至今). 科研方向 ? 黑色素合成酶结构与功能研究:酪氨酸酶的结构与具美白活性作用的抑制剂研 究;
天然产物对黑色素合成的抑制作用与黑色素瘤细胞增殖的影响研究. ? 海洋无脊椎动物功能酶类研究:南极磷虾、脊尾白虾等海洋无脊椎动物精氨酸 激酶活性功能研究;
虎斑乌贼精氨酸激酶与环境应激关系研究. ? 肤色调控关键基因与酶活性调控研究:中华鳖体色性状相关基因与酶的相互作 用与调控研究. 论文及著作(2000C 2016) 1.Yue-Xiu Si, Jinhyuk Lee, Shang-Jun Yin, Xiao-Xu Gu, Yong-Doo Park, and Guo- Ying Qian. 2015. The Inhibitory Effects of Cu2+ on Exopalaemon carinicauda Arginine Kinase via Inhibition Kinetics and Molecular Dynamics Simulations. Applied Biochemistry and Biotechnology. 176: 1217-1236. 2.Yue-Xiu Si, Xiao-Xu Gu, Yan Cai, Shang-Jun Yin, Jun-Mo Yang, Yong-Doo Park,Jinhyuk Lee, and Guo-Ying Qian. 2015. Molecular dynamics simulation integrating study for Cr3+-binding to arginine kinase. Process Biochemistry. 50: 1363- 1371. 3.Yue-Xiu Si, Jin-Jie Song, Nai-Yun Fang, Wei Wang, Zhi-Jiang Wang, Jun-Mo Yang, Guo-Ying Qian, Shang-Jun Yin, and Yong-Doo Park. 2014. Purification, characterization, and unfolding studies of arginine kinase from Antarctic krill. International Journal of Biological Macromolecules. 67: 426-432. 4.Yue-Xiu Si, Sunyoung Ji, Nai-Yun Fang, Wei Wang, Jun-Mo Yang, Guo-Ying Qian, Yong-Doo Park, Jinhyuk Lee, and Shang-Jun Yin. 2013. Effects of piperonylic acid on tyrosinase: Mixed-type inhibition kinetics and computational simulations. Process Biochemistry. 48: 1706-1714. 5.Yue-Xiu Si, Sunyoung Ji, Wei Wang, Nai-Yun Fang, Qing-Xin Jin, Yong-Doo Park, Guo-Ying Qian, Jinhyuk Lee, Hong-Yan Han, and Shang-Jun Yina. 2013. Effects of boldine on tyrosinase: Inhibition kinetics and computational simulation. Process Biochemistry. 48: 152-161.