PDF《Pure Gonadal Dysgenesis》

1 shows the H-Y antigen levelsin

41 patients affected by pure gonadal dys- genesis. Among

21 male-range H-Y antigen patients,

14 (67%)were reported to have gonadal tumors and

9 (43%) to be ~irilized.'

~-~'

There were five tumors and two viril- izationsin the seven caseswith intermediate H-Y antigen levelsreported in the current and two previous Only one tumor and one slight virilization were found among the

13 female-range ?3-Y antigen patients de-

1313 1314 CANCER April

1 1986 Vol.

57 TABLE I. 46,XY Pure Gonadal Dysgenesis: Relation Between H-Y Antigen, Gonadal Tumors, and Virilization:Review of

41 Cases No. of No. with H-Y antigen Authors subjects gonadal tumor No. with virilization Results Within the Dorus et nl.I'

(1977)

1 male range Moreira-Filho et aLi4 (1979)

2 Nazareth et a1. (1979)

1 Wolf16 (1979)

7 Jones et al. (1979)

2 Wachtel et a1.I8(1980)

5 Villanueva et nl.l9 (1984) Warner et dZ0 (1985)

2 1 Intermediate Wolfi6(1979)

2 2 Rao efal. (1981)

2 0 Amice (current report)

3 3

21 cases:

14 with tumor (67%)

9 virilized (43%) I

7 cases: I

0 2 virilized (29%)

5 with tumor (71%) Within the Gosh et ~

1 . ~ ~ (1978)

3 0

0 female Wolf16(1979)

3 0

0 range Hersh et aLZ3 (1980)

2 0

0 13cases: Moreira-Filhoefai.24 (1982)

1 0

0 I with tumor (8%) Warner el aL (1985)

1 1

0 1 slightlyvirilized (8%) Amice (current report)

3 0

1 (Slightclitoromegaly) scribed in our series and in earlier report^A re- lation between ........