PDF《Most Compact》

DASbox? Mini Bioreactor System for cell culture and microbiology Most Compact Parallel operation to shorten your time-to-market The smart design of the Eppendorf DASbox makes the 4-fold units ideal for parallel processing of up to

24 bioreactors.

Together with the DASware? software solutions, the DASbox supports process development following the Quality by Design (QbD) approach by providing comprehensive information management, integration of third-party analyzers, and Design of Experiments (DoE) tools as well as remote access. Parallel Process Development Epitome of compact: A 24-fold DASbox system takes up only 1.8 m (6 ft) of bench space. Compact design and small working volumes save lab space and valuable resources Lab space is critical: The DASbox requires only 7.5?cm (3?in) of bench space per bioreactor maximizing use of lab space while being expandable in 4-fold unit increments to increase capacity as needed. Small working volumes of

60 C 250?mL make it a perfect fit for clone/cell line screening, media optimization and small scale process development. One solution for all: fermentation and cell culture Suitable for microbiology and cell culture, the DASbox features advanced process control and precise monitoring of all critical process parameters. DASbox? single-use solutions: the BioBLU? 0.3 The Eppendorf BioBLU 0.3 Single-Use Vessels for use with the DASbox offer a proven rigid-walled single-use bioreactor portfolio―with vessels for cell culture and microbial applications, including high cell density fermentation and cultivation of stem cells. As the smallest member of the BioBLU single-use vessel family the BioBLU 0.3 allows for scalability from

65 mL up to 40?L working volume. Autoclavable glass bioreactors BioBLU 0.3 Single-Use Vessels Fermentation ? ? Suspension cells ? ? Stem cells ? ? BioBLU 0.3c for cell culture BioBLU 0.3f for microbiology Watch our video: www.eppendorf.com/dasbox-video Integrated Feeding and Monitoring Variable speed pumps and standard pH and DO sensors (redox or level options and optical pH sensors available) Small, but powerful. TMFC Gassing Integrated mass flow- controlled gas mixing system for continuous mixing of air, N2 , O2 and CO2 LC Color Display All vessels and parameters at a glance. Advanced Temperature Control Liquid-free temperature control unit for easy handling Technical data DASbox? Mini Bioreactor System for Cell Culture DASbox? Mini Bioreactor System for Microbiology Parallel bioreactors up to

24 up to

24 Software DASware control, other DASware optional DASware control, other DASware optional Vessels Glass and single-use vessels Glass and single-use vessels Working volumes

60 C

250 mL (glass)/100 mL C

250 mL (single-use)

60 C

250 mL (glass)/65 C

250 mL (single-use) Drive Overhead drive Overhead drive Impellers Marine (glass)/pitched blade (single-use) Rushton-type Agitation speed ranges

20 C 2,500 rpm (glass)/20 C

500 rpm (single-use)

20 C 2,500 rpm (glass)/20 C 2,000 rpm (single-use) Temperature control Liquid-free heating and cooling (Peltier) Liquid-free heating and cooling (Peltier) Standard temperature range

10 C 60°C at 25°C RT

10 C 60°C at 25°C RT Feeding lines per vessel

2 (standard)/4 (optional)

2 (standard)/4 (optional) Standard feed rates (depending on tube diameter) 0.3 C 9.5 mL/h to

13 C

420 mL/h 0.3 C 9.5 mL/h to

13 C

420 mL/h Gas flow control TMFC;

overlay and/or sparger TMFC Standard gas mixing Air, N2 , O2 and/or CO2 Air, N2 , O2 and/or CO2 Standard gas flow rates 0.04 C

5 sL/h, 0.04 C 3.5 sL/h CO2 0.2 C