PDF《刘志峰简介》

刘志峰简介 刘志峰,教授,硕士生导师,现任烟台大学药学院副 院长, 中国毒理学会理事, 中国毒理学会药物毒理与安全评 价专业委员会委员, 山东省毒理学会副理事长, 山东省动物 学会副理事长, 烟台市政协委员, 烟台大学九三学社副主委, 山东绿叶药物安全评价中心主任.

1982 年毕业于泰山医学院医疗系,1989 年毕业于军事 医学科学院, 获医学硕士学位. 在烟台大学药学院教授毒理 学,2000 年成功组建山东绿叶新药安全性评价中心,长期从事新药的安全性评 价、药物作用及其机理的研究.主持

4 项山东省科技攻关课题,1 项国家课题, 参与省部级和国家级课题

6 项.获得山东省科技进步奖

3 项,山东省教学研究成 果奖

2 项,

2008 年获山东省科技发明二等奖,先后申报国家发明专利

20 余项, 其中已授权

5 项.近年来发表科研论文

20 余篇. 近几年发表的部分科研论文 1. Zhifeng Liu, Ke liu et al. The Subchronic Toxicity of Hydroxysafflor Yellow A of

90 Days Repeatedly Intraperitoneal Injections in Rats. Toxicology. 2004;

203/1-3 pp. 139-143 2. 刘志峰,李大磊,李春梅,李敏,刘珂.血清标本溶血对大鼠血液生化指标的影响,毒 理学杂志.2006,20(6):392~393 3. Tian J, Li G, Liu Z, Zhang S, Qu G, Jiang W, Fu F. ND-309, a novel compound, ameliorates cerebral infarction in rats by antioxidant action. Neurosci Lett. 2008;

442(3):279-83 4. Tian J, Li G, Liu Z, Fu F. Hydroxysafflor yellow A inhibits rat brain mitochondrial permeability transition pores by a free radical scavenging action. Pharmacology. 2008;

82 (2):121-6. 5. Tian J, Fu F, Li G, Wang Y, Gao Y, Liu Z, Zhang S. SMND-309, a novel derivate of salvianolic acid B, ameliorates cerebral infarction in rats: characterization and role. Brain Res. 2009;

1263:114-21. 6. Tian J, Li G, Zhang S, Gao Y, Jiang W, Fu F, Liu Z.SMND-309, a novel derivate of salvianolic acid B, attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons. Basic Clin Pharmacol Toxicol. 2009;

104(2):176-84. 7. Tian J, Zhang S, Li G, Liu Z, Xu B. 20(S)-ginsenoside Rg3, a neuroprotective agent, inhibits mitochondrial permeability transition pores in rat brain. Phytother Res. 2009:486-91. 8. Li G, Gao Y, Li S, Li C, Zhu X, Li M, Liu Z. Study on toxicity of danshensu in beagle dogs after 3-month continuous intravenous infusion. Toxicol Mech Methods. 2009;

19 (6-7): 441-6. 9. Tian J, Fu F, Li G, Gao Y, Zhang Y, Meng Q, Li C, Liu F. Protections of SMND-309, a novel derivate of salvianolic acid B, on brain mitochondria contribute to injury amelioration in cerebral ischemia rats. Phytomedicine.

2009 (8):726-33. 10. Li C, Liu Z, Tian J, Li G, Jiang W, Zhang G, Chen F, Lin P, Ye Z,Protective roles of Asperosaponin VI, a triterpene saponin isolated from Dipsacus asper Wall on acute myocardial infarction in rats. Eur J Pharmacol.

2009 Nov 10. [Epub ahead of print]