PDF《杨春龙个人简介_杨春龙》

杨春龙/教授 院系化学系 性别男从事专业 有机化学;

农药学 学位博士 学历研究生 毕业院校 南京农业大学 职称教授 职务电话025-84395207 电子邮箱 ycl@njau.

edu.cn 研究方向 药物分子设计与合成;

新农药创制 个人简介 男,博士,教授,博士生导师.江苏省青蓝工程青年骨干教师培养对象,南京农业大学农药 创制中心主任.研究方向是以天然活性化合物为先导,设计并合成新型高效、低毒、无公害 绿色农药,侧重于仿生型杀菌剂和除草剂的研发.研究内容包括新型绿色农药分子设计、药 物合成、结构表征、生物活性评价、构效关系分析、作用机制探索、剂型研制.先后主持国 家自然科学基金、国家

863 计划、国家科技支撑计划、中央高校基本科研业务费专项、江苏 省科技支撑项目、江苏省自然科学基金、江苏省农业科技自主创新资金等科研项目.承担过 草甘磷、戊环唑、甲环唑、丙环唑、S,S-氰戊菊酯、烯唑醇、烯效唑等

10 多个农药品种的 研发工作.申请国家发明专利

26 项,其中

13 项获得授权.发表学术论文

65 篇,其中 SCI 收录

34 篇. 科研项目 1. 国家自然科学基金, 含取代苯肼的 tetramic acid 先导物的结构优化、 杀菌活性及 3D-QSAR 研究,2018-2021,研究经费

60 万元,主持. 2. 国家重点研发计划(子课题),棉田广谱高效生物除草剂 丁羟咯酮 及衍生物新产品创 制,2017-2020,研究经费

20 万元,研究内容主持. 3. 江苏省农业科技自主创新资金项目,以赤霉病防控为核心技术的小麦区域化高产安全技 术方案,2015-2018,研究经费

30 万元,研究内容主持. 4. 中央高校基本科研业务费(重大专项),基于生物源活性分子先导的新农药创制―合理 设计、合成、生物活性与作用机制研究,2016-2018,研究经费

20 万元,参加. 5. 国家自然科学基金,基于天然产物 TeA 的新型吡咯啉酮类除草剂的设计、合成与筛选研 究,2011-2015,研究经费

62 万元,主持. 6. 十二五 国家科技支撑计划,绿色生态农药的研发与产业化―基于天然源先导物 Tenuazonic acid 的新型绿色生态除草剂的分子设计、合成及构效关系研究,2011-2015,研 究经费

30 万元,研究内容主持. 7. 江苏省科技支撑计划(农业部分),基于微生物源的创制杀菌剂氯肼烷酮及其对小麦赤 霉病的防控关键技术研究,2012-2015,研究经费

40 万元,主持. 8. 十二五 国家高技术研究发展计划(863 计划),植物生长调节剂、生物除草剂研究与产 品创制,2011-2015,研究经费

40 万元,研究内容主持. 9. 中央高校基本科研业务费,新型绿色农药的分子设计、生物活性及安全性评价研究, 2012-2014,研究经费

40 万元,主持. 所获奖项 1. 基于学生差异性发展的化学教学模式的改革与实践,南京农业大学教学成果一等奖, 2012. 2. 研究型大学背景下农业院校数理化公共基础课教学改革与创新,南京农业大学教学成果 一等奖,2011. 教学信息 讲授课程:农药化学、农药合成与加工实验、现代农药合成实验. 发表文章 [1] Wei-Jie Si, Xiao-Bin Wang, Min Chen, Meng-Qi Wang, Ai-Min Lu and Chun-Long Yang*. Design, synthesis, antifungal activity and 3D-QSAR study of novel pyrazole carboxamide and niacinamide derivatives containing benzimidazole moiety[J]. New Journal of Chemistry, 2019, 43: 3000-3010. [2] Xiaobin Wang, Zhengjiao Ren, Yudong Mei, Menghan Liu, Min Chen, Weijie Si, Chunlong Yang* and Yimin Song*. Design, synthesis, and antifungal activity of 3-(thiophen-2-yl)- 1,5-dihydro-2H-pyrrol-2-one derivatives bearing a carbonic ester group[J]. Journal of Heterocyclic Chemistry, 2019, 56: 165-171. [3] Ling-Xia Li, Jian Jiao, Xiao-Bin Wang, Min Chen, Xin-Can Fu, Wei-Jie Si and Chun-Long Yang*. Synthesis, characterization, and antifungal activity of novel benzo[4,5]imidazo[1,2- d][1,2,4]triazine derivatives[J]. Molecules, 2018, 23(4), 746. [4] Xiaobin Wang, Zhengjiao Ren, Mengqi Wang, Min Chen, Aiming Lu, Weijie Si, Chunlong Yang*. Design and synthesis of novel 3-(thiophen-2-yl)-1,5-dihydro-2H-pyrrol-2-one derivatives bearing a hydrazone moiety as potential fungicides[J]. Chemistry Central Journal, 2018, 12, 83, 1-12. [5] Wei-Jie Si, Min Chen, Xue-Lun Wang, Meng-Qi Wang, Jian Jiao, Xin-Can Fu, and Chun-Long Yang*. Synthesis and insecticidal activity of novel benzothiazole derivatives containing the coumarin moiety[J]. Arkivoc, 2018, vii: 86-99. [6] Xiaobin Wang, Mengqi Wang, Jinghua Yan, Min Chen, An Wang, Yudong Mei, Weijie Si, Chunlong Yang*. Design, synthesis and 3D-QSAR of novel quinazolin-4(3H)-one derivatives containing a hydrazide moiety as potential fungicides[J]. ChemistrySelect, 2018, 3: 10663-1069. [7] Jun-Jun Wang, Wei-Jie Si, Min Chen, Ai-Min Lu, Wei-Hua Zhang*, Chun-Long Yang*. Synthesis and fungicidal activity of phenylhydrazone derivatives containing two carbonic acid ester groups[J]. J. Pestic. Sci., 2017, 42(3): 84-92. [8] Wen-Qin Xu, Min Chen, Kun-Yao Wang, Zheng-Jiao Ren, Ai-Min Lu and Chun-Long Yang*. Synthesis, characterization, and antifungal activity of phenylpyrrole-substituted tetramic acids bearing carbonates[J]. Molecules, 2016, 21, 355. [9] Lizhi Zhang, Zhengjiao Ren, Aimin Lu, Zheng Zhao, Wenqin Xu, Qianqian Bao, Weijie Ding, Chunlong Yang*. Synthesis, biological activity and 3D-QSAR study of novel pyrrolidine-2,4-dione derivatives containing N-substituted phenylhydrazine moiety[J]. Chem. Res. Chin. Univ., 2015, 31(2): 228-234. [10] Chen Min, Yang Chun-Long*. Synthesis, crystal structure and biological activity of 5-(2-methylphenyl)-1,3,4-oxadiazol-2(3H)-one derivatives[J]. Chinese J. Struct. Chem., 2015, 34(2): 189-196. [11] Ying Hu, Li-Zhi Zhang, Zheng-Jiao Ren, Zheng Zhao, Wen-Qin Xu and Chun-Long Yang*. Synthesis and antifungal activity of novel furan-2,4-dione derivatives containing substituted phenylhydrazine moiety[J]. J. Chin. Chem. Soc., 2015, 62, 495-500. [12] Wang Xian-Feng, Chen Min, Zhang Li-Zhi, Zhao Zheng, Yang Chun-Long*. Synthesis, characterization and bioactivity of novel 5,6-dihydropyrrolo[3,4-c]pyrazol-4-(1H)one derivatives[J]. Heterocyclic Communications, 2015, 21: 361-366. [13] Ying Hu, Junjun Wang, Aimin Lu, Chunlong Yang*. Synthesis, characterization, antifungal evaluation and 3D-QSAR study of phenylhydrazine substituted tetronic acid derivatives[J]. Bioorg. Med. Chem. Lett., 2014, 24: 3772-3776. [14] Gui-Hua Lu, Hai-Bin Chu, Min Chen, Chun-Long Yang*. Synthesis and bioactivity of novel strobilurin derivatives containing the pyrrolidine-2,4-dione moiety[J]. Chinese Chemical Letters, 2014, 25: 61C64. [15] Min Chen, Xian-Feng Wang, Si-Si Wang, Yi-Xiao Feng, Feng Chen, Chun-Long Yang*. Synthesis, characterization and fungicidal activities of novel fluorinated 3,5-disubstituted- 4H-1,2,4-triazol-4-amines[J]. Journal of Fluorine Chemistry, 2012, 135: 323-329. [16] Bao Feng Han, Qing Ming Shi, Xian Feng Wang, Jian Bo Liu, Sheng Qiang, Chun Long Yang*. Synthesis and bioactivity of novel 3-(1-hydroxyethylidene)-5-substituted-pyrrolidine- 2,4-dione derivatives[J]. Chinese Chemical Letters, 2012, 23: 1023-1026. [17] Xiao-Qian Zheng, Bao-Feng Han,Xian-Feng Wang,Sheng Qiang, Chun-Long Yang*. Synthesis and bioactivity of novel (Z,E)-1-(substituted phenyl)-3-[α-(alkyloxyimino) -benzylidene]pyrrolidine-2,4-dione derivatives[J]. Heterocycl. Commun., 2011, 17(1-2): 73-78. [18] Xian-Feng Wang, Teng-Fei Si, Qing-Bin Li, Zhao-Yong Zhu, Xian-Jie Zhu, Sheng Qiang, and Chun-Long Yang*. Synthesis, characterization and biological activity of novel (5-RS,6- S)-5-sec-butyl-3-(1-substituted-amino)ethylidene-1H-pyrrolidine-2,4-diones[J]. ARKIVOC, 2010, (ii): 31-48. [19] Zhao-Yong Zhu, Xian-Feng Wang, Fan-Gui Meng, Qing-Bin Li, Xiao-Qian Zheng, Sheng Qiang, and Chun-Long Yang*. Synthesis, Characterization, and Biological Activities of Novel (Z)-3-((E)-1-(Alkyloxyimino)Ethyl)-5-Arylidene-4-Hydroxypyrroline-2-One Derivatives[J]. J. Heterocyclic Chem., 2010, 47: 1328........