PDF《饶志明》

9、饶志明,张术聪,夏海锋等. 一种γ-氨基丁酸的分离纯化工艺.(专利号: ZL201010167007.4)

10、饶志明,徐美娟,满在伟等. 一种高产L-精氨酸钝齿棒杆菌分批发酵优化工 艺.(专利号:ZL201410249335.7) Aminobutyric Acid from Glucose without Exogenous Cofactor by the Designed Corynebacterium glutamicum. Green Chemistry. 2014, 16(9): 4190-4197. (SCI, IF2017=8.586)

5、Man Zaiwei, Rao Zhiming*, Xu Meijuan, Guo Jing, Yang Taowei, Zhang Xian, Xu Zhenghong*. Improvement of the intracellular environment for enhancing L- arginine production of Corynebacterium glutamicum by inactivation of H2O2-forming flavin reductases and optimization of ATP supply. Metabolic Engineering. 2016, 38:310-321. (SCI, IF2017=7.674)

6、Shao Minglong, Zhang Xian, Rao Zhiming*, Xu Meijuan, Yang Taowei, Li Hui, Xu Zhenghong, Yang Shangtian. Efficient testosterone production by engineered Pichia pastoris co-expressing human 17β-hydroxysteroid dehydrogenase type

3 and Saccharomyces cerevisiae glucose 6-phosphate dehydrogenase with NADPH regeneration. Green Chemistry. 2016, 18(6):1774-1784. (SCI, IF2017=8.586)

7、Xian Zhang, Rongzhen Zhang, Teng Bao, Zhiming Rao*, Taowei Yang, Meijuan Xu, Zhenghong Xu, Huazhong Li*, Shangtian Yang. The rebalanced pathway significantly enhances acetoin production by disruption of acetoin reductase gene and moderate-expression of a new water-forming NADH oxidase in Bacillus subtilis. Metabolic Engineering. 2014, 23: 34-41. (SCI, IF2017=7.674)

8、Junxian Zheng, Taowei Yang, Junping Zhou, Meijuan Xu, Xian Zhang, Zhiming Rao*, Shangtian Yang. Efficient production of D-amino acid oxidase in Escherichia coli by a trade-off between its expression and biomass using N-terminal modification. Bioresource Technology. 2017, DOI: http://dx.doi.org/10.1016/j.biortech.2017.07.007 (SCI, IF2017=5.807)

9、Yang Taowei, Rao Zhiming*, Hu Guiyuan, Zhang Xian, Liu Mei, Dai Yue, Xu Meijuan, Xu Zhenghong, Yang Shangtian. Metabolic engineering of Bacillus subtilis for redistributing the carbon flux to 2,3-butanediol by manipulating NADH levels. Biotechnology for Biofuels. 2015, 8:129. (SCI, IF2017=5.497)

三、承担教学科研项目情况

四、获奖情况(含指导学生获奖) 主持包括国家863项目、国家973子课题、国家自然科学基金面上项目等在内的 省部级科研项目20余项,主要包括:

1、 国家863(2015AA021004):有机酸生物制造关键技术研究,2015-2017, 首席专家,168/864 万元,完成.

2、国家863(2007AA02Z207):低能耗高产精氨酸工程菌构建及其发酵优化, 2007-2010,负责,100 万元,完成.

3、科技部973(2012CB725202):用合成生物学方法构建生物基材料--微生物 基因组的优化,2012-2016,子课题负责人,80万元,完成.

4、教育部项目新世纪优秀人才支持计划项目:食品微生物代谢工程及其发酵调 控,2011-2013,50万元,完成.

5、江苏省杰出青年项目:棒杆菌高效合成L-精氨酸系统代谢工程改造及其发酵 调控关键技术研究,2015-2018,150万元,完成.

6、国家自然科学基金(31870066):LysR家族转录因子LrpG影响温度调控粘质 沙雷氏菌合成灵菌红素的分子机理研究,负责,70万元,2019-2022.

7、国家自然科学基金(31570085):基于组合生物学强化Mycobacterium neoaurum 降解植物甾醇侧链的代谢改造,2016-2019,负责,75万元,2016-2019.

8、国家自然科学基金(21276110):解淀粉芽孢杆菌2,3-丁二醇逆向转化3-羟 基丁酮的代谢机制,2013-2016,负责,78 ........