PDF《Amy Rebecca Bentley》

Amy Rebecca Bentley Center for Research on Genomics and Global Health National Human Genome Research Institute Building 12A, Room 4047,

12 South Drive, MSC 5635, Bethesda, MD

20892 amy.

[email protected] Current Appointment December

2016 to present: Staff Scientist, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD. Education March

2014 to December 2016: Research Fellow, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD. August

2010 to March 2014: Postdoctoral Fellow, Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD. January to August 2010: Division of Nutritional Sciences, Cornell University, Ithaca, NY. Postdoctoral Associate. January

2004 to January 2010: Cornell University, Ithaca, NY. Doctoral Program in Nutritional Sciences with Minors in Epidemiology and Population Genetics;

Dissertation Oxidant- Antioxidant Balance and Lung Outcomes: The Role of Nutrition, Genetic Susceptibility, and Cigarette Smoking August

2001 to May 2003: LaSalle University, Philadelphia, PA. BS in Nutrition May

2000 to May 2001: University of Pennsylvania, Philadelphia, PA. Coursework in Chemistry August

1992 to May

1995 &

August

1996 to May 1997: Guilford College, Greensboro, NC. BA in English with Minors in Spanish and International Studies August to December 1993: Study Abroad at Beijing University'

s Foreign Language Normal College, China August to December 1994: Study Abroad at University of Guadalajara, Mexico Training and Professional Experience April 2017: Judge, Postbac Poster Day, National Institutes of Health, Bethesda, MD May 2016: Lecturer on Genomic Variation in Health Disparities for Applications of Genomics to Public Health Challenges course offered at NHGRI, NIH, Bethesda, MD April 2016: Judge, Postbac Poster Day, National Institutes of Health, Bethesda, MD November 2015: Introduction to Python Programming, Center for Information Technology, NIH September 2015: Scientists Teaching Science, Office of Intramural Training and Education, NIH April 2015: Judge, Postbac Poster Day, National Institutes of Health, Bethesda, MD December 2014: Sequence Analysis Workshop, University of Michigan Center for Statistical Genetics May 2014: Judge, Postbac Poster Day, National Institutes of Health, Bethesda, MD April 2014: Judge, American Society of Human Genetics DNA Day Essay Contest. May 2013: Instructor, Early Bird Session ( An introduction to the analysis of sequence data ), African Society of Human Genetics Meeting, Accra, Ghana. May 2013: Judge, Postbac Poster Day, National Institutes of Health, Bethesda, MD December 2012: Short Course on Next-Generation Sequencing: Technology &

Statistical Methods, University of Alabama at Birmingham June 2012: Careers in Grants Management, National Institutes of Health, Bethesda, MD May 2011: Judge, Postbac Poster Day, National Institutes of Health, Bethesda, MD May 2011: UNIX 101, National Human Genome Research Institute, Bethesda, MD March 2011: Genetic Association Course, Baylor College of Medicine, Houston, TX February 2011: National Center for Biotechnology Information'

s Discovery Workshop, NIH, Bethesda, MD January

2005 to December 2006: Undergraduate Student Mentor, Cornell University, Ithaca, NY January

2004 to December 2005: Teaching Assistant, Nutrition/Dietetics Courses, Cornell University, Ithaca NY June

2003 to September 2003: Nutrition Educator, Philadelphia Corporation for the Aging, Philadelphia PA June

2002 to June 2003: Student Nutritionist, Women, Infants, and Children, Philadelphia, PA October

1998 to June 2002: Administrative Coordinator, English Language Programs, University of Pennsylvania, Philadelphia, PA January

1997 to May 1997: Teaching Assistant, English, Guilford College, Greensboro, NC Fellowships and Honors October 2017: Recipient of NHGRI GREAT Award for Diversity and Inclusion as part of the Rotimi Diversity team For efforts in promoting diversity and inclusion in genomic research. October 2017: Recipient of NHGRI GREAT Award for Diversity and Inclusion as part of the GRASP team For major advances in understanding the genetic basis for disparities in the frequency and severity of scleroderma, a life-threatening autoimmune disease, in African Americans. November 2016: National Human Genome Research Institute'

s Intramural Research Award June 2011: Full scholarship to attend the Human Genome Variation

2011 meeting to present GWAS of serum ion concentrations in African Americans May 2010: Selected to represent all graduating Ph.D. students for May

2010 Commencement Ceremony November 2009: Selected for the NIH'

s National Graduate Student Research Festival January

2006 to December 2009: National Institutes of Health Training Grant Recipient May 2003: Top Graduate in Nutrition, LaSalle University, Philadelphia, PA August

2002 to May 2003: American Dietetics Foundation Scholarship August

2001 to May 2003: Founders Scholarship, LaSalle University, Philadelphia, PA August

1992 to May 1997: Full Merit Scholarship, Guilford College, Greensboro, NC August

1992 to May 1997: National Merit Scholarship Professional Memberships June

2011 to present: American Society of Human Genetics August

2005 to October 2007: Treasurer, Nutrition Graduate Student Organization, Cornell University, Ithaca, NY August

2002 to May 2003: Vice President: Student Nutrition Club, LaSalle University, Philadelphia PA Publications Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR*, et al. A Large-Scale Multi-ancestry Genome-wide study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet.

2018 Mar 1;

102 (3):375-400. *Co-first author Utumatwishima JN, Chung ST, Bentley AR, Udahogora M, Sumner AE. Reversing the tide C diagnosis and prevention of T2DM in populations of African descent. Nat Rev Endocrinol.

2018 Jan;

14(1): 45-56. Rotimi CN, Bentley AR, Doumatey AP, Chen G, Shriner D, Adeyemo A. The genomic landscape of African populations in health and disease. Hum Mol Genet. 2017;

26(R2): R225-R236. Bentley AR, Callier S, Rotimi CN. Diversity and inclusion in genomic research: why the uneven progress? J Community Genet.

2017 Oct;

8(4):255-266. PMC5614884 Bentley AR, Rotimi CN. Interethnic Differences in Serum Lipids: Implications for Cardiometabolic Disease Risk in African Ancestry Populations. Global Heart. 2017;

12(2):141-150. PMC5582986 Chen G, Zhang Z, Adebamowo SN, Liu G, Adeyemo A, Zhou Y, Doumatey AP, Wang C, Zhou J, Yan W, Shriner D, Tekola-Ayele F, Bentley AR, Jiang C, Rotimi CN. Common and rare exonic MUC5B variants associated with type

2 diabetes in Han Chinese. PLoS One.

2017 Mar 27;

12(3). PMC5367689 Chen G, Doumatey AP, Zhou J, Lei L, Bentley AR, Tekola-Ayele F, Adebamowo SN, Baker JL, Fasanmade O, Okafor G, Eghan B Jr, Agyenim-Boateng K, Amoah A, Adebamowo C, Acheampong J, Johnson T, Oli J, Shriner D, Adeyemo AA, Rotimi CN. Genome-wide analysis identifies an African-specific variant in SEMA4D associated with body mass index. Obesity (Silver Spring).

2017 Apr;

25(4):794-800. PMC5373947 Baker JL, Shriner D, Bentley AR, Rotimi CN. Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa. Pharmacogenomics J.

2017 Mar;

17(2):112-120. PMC5380847 Liu C-T, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MCY, Hivert M-F, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, Li M, Lipovich L, Rybin DV, Taylor KD, Agyemang C, Palmer ND, Cade BE, Chen W-M, Dauriz M, Delaney JAC, Edwards TL, Evans DS, Evans MK, Lange LA, Leong AS, Liu J, Liu Y, Nayak U, Patel SR, Porneala BC, Rasmussen-Torvik LJ, Snijder MB, Stallings S, Tanaka T, Yanek LR, Zhao W, Becker DM, Bielak LF, Biggs ML, Bottinger EP, Bowden DW, Chen G, Correa A, Couper DJ, Crawford DC, Cushman M, Eicher JD, Fornage M, Franceschini N, Fu Y-P, Goodarzi MO, Gottesman O, Hara K, Harris TB, Jensen RA, Johnson AD, Jhun MA, Karter AJ, Keller MF, Kho AN, Kizer JR, Krauss R, Langefeld CD, Li X, Liang J, Liu S, Lowe WL, Mosley TH, North KE, Pacheco JA, Peyser PA, Patrick AL, Rice KM, Selvin E, Sims M, Smith JA, Tajuddin SM, Vaidya D, Wren MP, Yao J, Zhu X, Ziegler JT, Zmuda JM, Zonderman AB, Zwinderman AH, AAAG Consortium, CARe Consortium, COGENT Consortium, eMERGE Consortium, MEDIA Consortium, Adeyemo A, Boerwinkle E, Ferrucci L, Hayes MG, Kardia SLR, Miljkovic I, Pankow JS, Rotimi CN, Sale MM, Wagenknecht LE, Arnett DK, Chen I, Nalls MA, MAGIC Consortium, Province MA, Kao WHL, Siscovick DS, Psaty BM, Wilson JG, Loos RJF, Dupuis J, Rich SS, Florez JC, Rotter JI, Morris AP, Meigs JB. Trans-ethnic Meta-Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. Am J Hum Genet.

2016 July;

99(1);

56-75. PMC5005440 Adebamowo SN, Adeyemo AA, Tekola-Ayele F, Doumatey AP, Bentley AR, Chen GJ, Zhou J, Shriner D, Fasanmade, OA, Okafor G, Eghan B Jr, Agyenim-Boateng K, Adeleye J, Balogun W, Amoah AG, Owusu S, Acheampong J, Johnson T, Oli J, Adebamowo CA, Rotimi CN. Impact of Type

2 Diabetes on Impaired Kidney Function in Sub-Saharan African Populations. Front Endocrinol, 2016;

7(50). PMC4884893 Shriner D, Kumkhaek C, Doumatey AP, Chen GJ, Bentley AR, Charles BA, Zhou J, Adeyemo A, Rodgers GP, Rotimi CN. Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans. BMC Medical Genetics, 2015;

16(103). PMC4684912 Adeyemo AA, Tekola-Ayele F, Doumatey AP, Bentley AR, Chen G, Huang H, Zhou J, Shriner D, Fasanmade O, Okafor G, Eghan B Jr, Agyenim-Boateng K, Adeleye J, Balogun W, Elkahloun A, Chandrasekharappa S, Owusu S,Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C, Collins F, Dunston G, Rotimi CN. Evaluation of Genome Wide Association Study Associated Type

2 Diabetes Susceptibility Loci in Sub Saharan Africans. Front Genet, 2015;

6(335). PMC4656823 Shriner D, Bentley AR, Doumatey AP, Chen G, Zhou J, Adeyemo A, Rotimi CN. Phenotypic variance explained by local ancestry in admixed African Americans. Front Genet, 2015;

6(324). PMC4625172 Tekola-Ayele F, Doumatey AP, Shriner D, Bentley AR, Chen G, Zhou J, Fasanmade O, Johnson T, Oli J, Okafor G, Eghan BA Jr., Agyenim-Boateng K, Adebamowo C, Amoah A, Acheampong J, Adeyemo A, Rotimi CN. Genome-wide association study identifies African- ancestry specific-variants for metabolic syndrome. Mol Genet Metab, 2015;

116(4):305-313. PMID

26507551 Chen G, Yuan A, Shriner D, Tekola-Ayele F, Zhou J, Bentley AR, Zhou Y, Wang C, Newport MJ, Adeyemo A, Rotimi CN. An Improved Fst Estimator. PLOS One, 2015;

10 (8): e0135368. PMC4552798 Bentley AR, Divers J, Shriner D, Doumatey AP, Gutierrez OM, Adeyemo AA, Freedman BI, Rotimi CN. APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans. BMC Genomics, 2015;

16:421. PMC4448293 Bentley AR, Chen G, Shriner D, Doumatey AP, Zhou J, Huang H, Mullikin JC, Blakesley RW, Hansen NF, Bouffard GG, Cherukuri PF, Maskeri B, Young AC, Adeyemo AA, Rotimi CN. Gene-based Sequencing Identifies Lipid-Influencing Variants with Ethnicity-Specific Effects in African Americans. PLOS Genetics, 2014;

10(3):e1004190 PMC3945436 Tang W, Bentley AR, Kritchevsky SB, Harris TB, Newman AB, Bauer DC, Meibohm B, and Cassano PA for the Health ABC Study. Genetic Variation in Antioxidant Enzymes, Cigarette Smoking and Longitudinal Change in Lung Function. Free Radic Biol Med.

2013 Oct;

63:304-12. PMC4060265 Hancock DB*, Soler Artigas M*, Gharib SA*, Henry A*, Manichaikul A*, Ramasamy A*, Loth DW*, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott ........