PDF《20152016 年河北省腹泻散发病例中诺如病毒》

第10 卷第7期食品安全质量检测学报Vol.

10 No.

7 2019 年4月Journal of Food Safety and Quality Apr. ,

2019 基金项目: 河北省科技支撑计划项目(15277778D) Fund: Supported by the Hebei Science and Technology Program (15277778D) *通讯作者: 申志新, 主任技师, 主要研究方向为微生物学检验.E-mail: [email protected] *Corresponding author: SHEN Zhi-Xin, Chief Technician, Hebei Provencial Center Control and Prevention, No.97, Huai'an East Road, Shijiazhuang 050021, China. E-mail: [email protected] 2015?2016 年河北省腹泻散发病例中诺如病毒 感染的流行病学特征分析 张淑红

1 , 白雪1,蒋瑞萍

2 , 陈凤阳

3 , 时晨4,何旭鑫

5 , 董晓枫

6 , 申志新 1* (1. 河北省疾病预防控制中心, 石家庄 050021;

2. 石家庄市疾病预防控制中心, 石家庄 050011;

3. 邢台市疾病预防控制中心, 邢台 054000;

4. 秦皇岛市疾病预防控制中心, 秦皇岛 066000;

5. 承德市疾病预防控制中心, 承德 067000;

6. 沧州市疾病预防控制中心, 沧州 061001) 摘要: 目的 了解 2015?2016 年河北省腹泻散发病例中诺如病毒感染的流行病学特征.方法 收集

2015 年9月~2016 年12 月河北省部分医院肠道门诊腹泻病例便样本及流行病学相关资料, 采用 RT-PCR 方法检测 诺如病毒并进行数据分析.结果 在1240 样本中, 诺如病毒阳性

58 份, 阳性率为 4.68%;

诺如病毒阳性率 存在地域差异, 邢台地区阳性率最高为 10.08%;

全年均有散发病例但在冬春季节出现明显的发病高峰;

基 因型以 GⅡ型为主(4.28%), GI 型阳性率 0.40%;

易感人群为婴幼儿(0~6 岁)和老年组(66~), 其感染不存在性 别差异.结论 诺如病毒是河北省散发感染性腹泻的重要病原, 应加强对诺如病毒的监测, 并进一步研究其 变异, 为诺如病毒感染的预防和控制提供科学的依据. 关键词: 诺如病毒;

腹泻;

流行病学 Analysis on the epidemiological characteristics of norovirus diarrhea in Hebei province in 2015?2016 ZHANG Shu-Hong1 , BAI Xue1 , JIANG Rui-Ping2 , CHEN Feng-Yang3 , SHI Chen4 , HE Xu-Xin5 , DONG Xiao-Feng6 , SHEN Zhi-Xin1* (1. Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang 050021, China;

2. Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang 050011, China;

3. Xingtai Center for Disease Control and Prevention, Xingtai 054000, China;

4. Qinhuangdao Center for Disease Control and Prevention, Qinhuangdao 066000, China;

5. Chengde Center for Disease Control and Prevention, Chengde 067000, China;

6. Cangzhou Center for Disease Control and Prevention, Cangzhou 061001, China) ABSTRACT: Objective To understand the epidemiological characteristics of norovirus infection in sporadic diarrhea cases in Hebei province in 2015?2016. Methods The diarrhea stool samples and epidemiological related data from September

2015 to December

2016 in the intestinal clinic were collected, and norovirus was detected and classified by RT-PCR. Results A total of

58 (4.68%) positive specimens were detected among

1240 sporadic cases of acute diarrhea;

the positive rate of norovirus varied by region, and the highest positive rate of Xingtai was 10.08%. There were sporadic cases throughout the year, but there were obvious peak in winter and spring. The genotype was mainly GⅡtype

2074 食品安全质量检测学报第10 卷(4.28%), GI type positive rate was 0.40%. The susceptible population was infants (0~6) and the elderly group (66~), and there was no difference infection in gender. Conclusion Norovirus is an important pathogen of infections diarrhea in Hebei province. The monitoring of norovirus should be strengthened, and its variation should be further studied to provide a scientific basis for the prevention and control of norovirus infection. KEY WORDS: norovirus;