PDF《丝氨酸组酰胺对 5c -pTpTpCp-3c》

2. College of S cience , Sou th China Agriculture University, Guangzhou 510642, China;

3. Institute of B iophysics , Ch inese A cademy of Sciences , B eijing

100101 , Ch ina) Abstract A quantu m chem istry calcu lation w as carried out to study them echanism of 5c -pTpTpCp-3c cleav - age by theL /D-Ser -H ism. The effectivemolecu lar recogn ition betw een L /D-Ser -H ism and DNA through mu lt- i hydrogen-bonds and the correspond ing structural parameters w ere ob tained . The results could be used to ex - plain the mechan ism ofDNA cleavage by L /D-Ser -H ism. K eywords L /D-Ser -H ism;

5c -pTpTpCp -3csegm en;

t C leavage mechan ism ( Ed . : Y, I)

1569 No .

8 刘华鼐等: 丝氨酸组酰胺对 5c -pTpTpCp-3c 片段切割作用的量子化学计算 ........